Toradol is a powerful NSAID that doctors prescribe for short‑term pain relief after surgery or injury. If you’re wondering how it works, how to take it safely, and what risks to watch for, this guide has you covered.
TL;DR - Quick Takeaways
- Toradol (ketorolac) is a prescription NSAID used for moderate to severe pain, usually for up to 5 days.
- It comes as an oral tablet, injectable, or eye drops; oral dose is 10mg every 4‑6hours.
- Major side effects include stomach bleeding, kidney problems, and increased heart risk.
- Avoid using it with other NSAIDs, alcohol, or if you have ulcers, kidney disease, or heart failure.
- Call a doctor immediately if you notice black stools, severe stomach pain, or sudden swelling.
What is Toradol and How Does It Work?
Toradol is the brand name for ketorolac tromethamine, a non‑steroidal anti‑inflammatory drug (NSAID). Like ibuprofen or naproxen, it blocks the enzyme cyclooxygenase (COX) which produces prostaglandins-chemicals that cause pain, fever, and inflammation. By cutting down prostaglandin production, Toradol can knock out pain quickly, often within 30 minutes of a dose.
Because it’s more potent than typical over‑the‑counter NSAIDs, doctors reserve it for short bursts of pain-post‑operative soreness, kidney stone attacks, or severe migraine attacks when other meds haven’t helped. The drug’s potency also means it carries a higher risk of side effects, which is why FDA guidelines restrict use to a maximum of five days for oral or injectable forms.
Toradol is available in three main formulations:
Form | Strength | Typical Dose | Route | Frequency |
---|---|---|---|---|
Oral tablet | 10mg | 10mg | By mouth | Every 4‑6hrs (max 5 days) |
Injectable | 15mg/1mL | 15‑30mg | IV/IM | Every 6hrs (max 5 days) |
Ophthalmic drops | 0.5% | One drop per eye | Eye | Up to 4times daily |
Each form is chosen based on how fast you need relief and where the pain is located. For most adults, the oral tablet is the go‑to because it’s easy to take at home.
When and How to Use Toradol Safely
Because Toradol is strong, the safest use starts with checking whether you’re a good candidate. Below is a quick checklist you can run through before you fill the prescription:
- Do you have a history of stomach ulcers, GI bleeding, or recent surgery? If yes, avoid Toradol or use it only under strict medical supervision.
- Are you pregnant, especially in the third trimester? Toradol can harm the fetus and should be avoided.
- Do you have kidney disease, heart failure, or uncontrolled hypertension? The drug is cleared by the kidneys and can worsen these conditions.
- Are you taking other NSAIDs, blood thinners (warfarin, clopidogrel), or steroids? Combining them spikes bleeding risk.
- Are you over 65? Older adults are more susceptible to kidney and GI complications.
If you tick any of those boxes, discuss alternatives with your doctor-maybe acetaminophen, a short course of opioids, or a different NSAID with a lower risk profile.
Assuming you’ve cleared the checklist, here’s the step‑by‑step for taking oral Toradol correctly:
- Read the prescription label. Confirm the strength (usually 10mg tablets).
- Take the tablet with a full glass of water (8oz). Food can help protect your stomach, but a light snack is enough; don’t lie down right after.
- Set a timer for every 4‑6hours. Do not exceed 40mg in a 24‑hour period (or 60mg if you’re a “high dose” patient under close monitoring).
- Mark the start date on a calendar. Count five days and stop-no “just one more dose” extensions without doctor approval.
- If you miss a dose, take it as soon as you remember **only if** it’s more than 6hours before the next scheduled dose. Otherwise, skip it and resume the normal schedule.
For injectable Toradol, the process is usually handled in a clinic or hospital. The key safety points are the same-limit to five days, monitor kidney function labs, and watch for allergic reactions at the injection site.

Side Effects, Interactions, and When to Seek Help
Every medication has trade‑offs. With Toradol, the most common side effects are mild and include:
- Nausea or vomiting
- Headache
- Dizziness
- Minor stomach upset
More serious, though less frequent, complications demand immediate attention:
- Black or tarry stools (sign of GI bleeding)
- Severe stomach or abdominal pain
- Sudden swelling of the legs or face (possible allergic reaction)
- Decreased urine output or swelling in the ankles (kidney issues)
- Chest pain, shortness of breath, or rapid heartbeat (cardiovascular risk)
Drug‑drug interactions are a big deal with NSAIDs. Here’s a quick interaction cheat‑sheet:
Drug/Class | Interaction Risk | Result |
---|---|---|
Warfarin / other anticoagulants | High | Increased bleeding |
ACE inhibitors, ARBs, diuretics | Moderate | Reduced kidney function |
Other NSAIDs (ibuprofen, naproxen) | High | GI ulcers, bleeding |
Selective serotonin reuptake inhibitors (SSRIs) | Moderate | Bleeding risk |
Alcohol | Moderate | Stomach irritation, liver strain |
When you start Toradol, your doctor may order baseline labs-creatinine, BUN, liver enzymes-to ensure your organs can handle the drug. Repeat labs after a few days are standard if you’re on the injectable form.
**What to do if something feels off**:
- Stop the medication immediately.
- Call your prescribing doctor or a pharmacist for guidance.
- If you notice any sign of severe bleeding (black stools, vomiting blood), call emergency services right away.
- For mild stomach upset, try taking the next dose with food and a proton‑pump inhibitor (e.g., omeprazole) if your doctor approves.
Putting It All Together - Practical Checklist
- Confirm you have a valid prescription; Toradol isn’t available over the counter.
- Run the health‑history checklist (ulcers, kidney, heart, pregnancy).
- Mark a five‑day limit on your calendar; never exceed it without a doctor’s okay.
- Take each tablet with water and a light snack; avoid lying down for 30minutes.
- Track side effects in a simple log-date, dose, symptom.
- Know the red‑flag symptoms (black stools, severe pain, swelling) and act fast.
Mini‑FAQ
- Can I take Toradol with ibuprofen? No. Combining NSAIDs greatly raises bleeding risk.
- Is Toradol safe for kids? It’s approved for children over 2years but only in injectable form and under strict medical supervision.
- How quickly does it work? Oral tablets start relieving pain within 30‑60minutes; injectable works in about 15minutes.
- What if I need pain relief longer than five days? Discuss alternatives with your doctor-maybe a switch to a less potent NSAID or a non‑NSAID regimen.
- Can I drink alcohol while on Toradol? It’s best to avoid alcohol because it can irritate the stomach lining and increase bleed risk.

Next Steps & Troubleshooting
If you’ve just gotten your prescription, set a reminder on your phone for the first dose, and create a short “pain diary” to note how well the medication controls your symptoms. If after 48hours you still feel significant pain, contact your doctor-there might be a dosage adjustment or a switch needed.
For those who experience mild stomach upset, ask your provider about adding a low‑dose proton‑pump inhibitor (PPI) or an H2 blocker. If you notice any swelling or shortness of breath, stop the drug and seek urgent care.
Remember, Toradol is a short‑term tool, not a long‑term solution. Proper use can give you quick relief and get you back to daily life without the dreaded side effects.