Avanafil (Stendra): Fast-Acting ED Medicine You Should Know

Need an ED option that kicks in quickly? Avanafil—sold as Stendra—is one of the faster oral ED drugs. Many people pick it because it can start working in as little as 15–30 minutes and usually lasts several hours. Below you’ll find clear, practical info to help you decide if avanafil might fit your needs.

How avanafil works and how to use it

Avanafil is a PDE5 inhibitor. That means it relaxes blood vessels in the penis so blood flows in during sexual arousal. It won’t cause an erection without sexual stimulation.

Common doses are 50 mg, 100 mg, and 200 mg. A typical starting dose is 100 mg taken about 15–30 minutes before sex. Your doctor may lower it to 50 mg or raise it to 200 mg depending on how you respond and your health. Don’t take more than one dose a day.

Food can slow how fast it works. High‑fat meals may delay onset, so take it on an emptier stomach if you want faster effect. Grapefruit juice and some supplements can affect drug levels, so mention those to your prescriber.

Safety, side effects, and interactions

Side effects are usually mild: headache, flushing, nasal congestion, and dizziness are the most common. Less common but serious problems include sudden vision changes (NAION), sudden hearing loss, and priapism—an erection lasting longer than four hours. Seek medical help right away for those.

Don’t use avanafil with nitrates (often used for chest pain). Combining them can cause a dangerous drop in blood pressure. Be cautious with alpha‑blockers and medicines that affect CYP3A4 (like ketoconazole or certain HIV drugs); these can raise or lower avanafil levels. Tell your doctor about all prescriptions, over‑the‑counter meds, and supplements.

If you have severe liver or kidney problems, heart disease, or recent stroke, talk to your doctor before trying avanafil. Your doctor will weigh risks and may suggest dose changes or a different treatment.

Buying tip: always get a prescription. Use a licensed pharmacy with clear contact details and verified reviews. Extremely low prices or pharmacies that skip prescriptions are red flags. If you need help comparing options or finding a reputable online pharmacy, the guides on EmpowerPharmacy.com can point you in the right direction.

Want a fast ED option with relatively few side effects? Avanafil is worth discussing with your clinician. Bring up your current meds, heart health, and how quickly you want the drug to act—those details help pick the right dose and timing.

If you have questions about interactions or safe buying, ask your pharmacist or doctor. They can give advice tailored to your health and keep you safe while getting the results you want.